Newbie AI and TRT please help

D

dsmhacker

New member
Hey folks, I have been on TRT now for about 9 months, mostly wasted on Androgel. I have been on test-cyp for about 4 months.

Labs were pretty bad, E2 was sky high. I was originally prescribed Arimidex, but seemed to be an over responder. Crashing my E2 even with 1/3 the dose.

I have been now using Exemestane, and still cant seem to get my AI dosage right, and i'm wondering f any one has any suggestions.

I am currently taking 50 mg test cyp 2x per week. Friday and Sunday morning. I take my AI when I start feeling edgy, emotional. But as soon as I take it, my libido, ED seem to be affected, but emotionally, and mentally I feel good, not like im on top of the world.

This is very frustrating. Can anyone shed some light on this?



Free Testosterone(Direct) 31.6 Range 8.7-25.1

Testosterone, Total, LC/MS 922.4 Range 348.0-1197.0

Dihydrotestosterone 20 Range L

Estradiol 18.6 Range 7.6-42.6
 
With the aormasian are you taking it with a fat source? It doesn't last as long other wise. What your dosage and how often. I had a hard time with adex too. It messed up my lipids and I crashed my e levels very easily. Is it by script or other means. Because then there's the are you sure it's legit and Aromasain.

The way it sounds like your dosing is playing catch up after the fact. Id suggest not letting e get up high in the first place. I wound also as I was working on proper dosing get labs so you know for a fact what doses work and don't.
 
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@ HammerT1, I just took 3 slices of cheese, and some potato chips, type 2 diabetes, so the few carbs is a lot for me. I am taking 1/8 of 25mg. Exemestane was prescribed by my GP.

Interesting fact, I waited 7 days from Adex, to Exemestane. On the 6night, I couldn't take how I felt anymore and took 1/8 dose of exemestane, labs the next morning, and E2 was 18.


@STAUNCHED427 I was taking .33 mg ground up in vodka.
 
You didn't mention your adex dosing frequency, big difference betwen .33mg monday and thursday or ED dosing.

AI's do get to work fast, I could feel stane pushing my e2 too low from borderline normal levels within 6 hours. They start blocking aromatase enzyme immediately so e2 should always start lowering off the bat.

Hmm how do you cut up the stane like that, halfs was hard enough for me lol.

Maybe getting some Liquid Adex/Stane and playing around with micro dosing could find what works for you,.
 
@STAUNCHED427, sorry don't quite remember my dosage, its been a while. I was taking EOD I think. I looked at getting liquid aromasin. but every time I went to buy, the site crashed.

I cut using a pill cutter, in 1/8ths its a major waste. 1/4ths are easy, but I am sue it crashes my E2.

Issues when not taking AI regularly emotional, and anxiety, difficulty in orgasm. Take AI and I get a bit emotionless, low libido, major ED.

Where can I get a liquid exemestane?
 
@STAUNCHED427 are you referring to Adex? I've switched over to Exemestane now taking 1/8 of a pill going to try EOD, but interesting. Can I use the same approach using exemestane?
 
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Yeah .33mg or .25mg Adex on injection day/12 hours after injection only not EOD (whatever really, won't be much difference in timing but T and therefore E2 levels start to rise come 12 hours).

Stane has a short half life, supposedly 9 hours in men not 24 like stated for women. I'd stick with the adex at the protocol I just mentioned and see how that works for you. Adex has a longer half life (~48 hours).
 
I am surprised you need an AI on 50mg of test every 3.5 days. Did you get your E2 lab (sensitive assay) on the testosterone dosing schedule?

If so, have you tried using DIM instead of an AI?
 
@Staunched427, thanks ill consider it. If I go back to Adex, is there a period of time I should wait after taking exemestane?

@Megatron28, E2 was 18.6 (not sure what sensitive assay is)I'll have to do some reading on DIM vs AI.

Thanks all for your support!
 
@Megtron28

Well that is kind of a long story. In short, wife was really giving me 200mg per week. Thinking it was only 100mg. Free T was over 50, T was 1195, E2 62.

Now back down to 100mg per week, for about 2 months now. I don't quite know what my E2 is at without AI. I caved the night before my labs and took 1/8 exemestane, cause I couldn't stand how I felt. That next morning after blood work, my E2 was 18.


So far since Saturday I have been taking 1/8 exemestane EOD, ad seem to be riding through pretty well.

Ill keep ya posted, i'm sure it will get jacked up soon.

Thanks all for your help and advice!!

-Lex
 
I re-read your post and you said you inject on Friday and Sunday morning, That is a frequency of EOD then E5D which is going to give you a swing in test levels throughout the week and consequently E2... I would change from Fri/Sun to Sunday Mornings and Wednesday Nights giving you roughly 82 hours between each inject. This could be the reason why your e2 is a little hard to control, in addition to being on 200mg a week when you should be on 100mg.
 
I wouldn't take an extras dose right before a test. You loose seeing what is really going on with your labs. If I was at 18 I'd feel like ass. Was the e test the estrogen sensitive test? If not might be off a bit. You may also want to get some extra tests so you can see if there is any or what your fluxes are.
When I've crashed my E, I felt worse and had just as many sides as if it was too high.

I did it once with adex and then being cheap and not tapping a new Aromasain bottle when I got towards the bottom. Basically I got way more med then I needed. I've often wondered how consistent pill were. I've worked manufacturing and there's always a variation. It just depends on how good that pharma manufacturing plant quality control is. I mean in terms of when one has to split a pill or quarter it to get right dosing. Before insurance screwed up me using an AI. (My adex was made by a compounding pharmacy and in capsule form) I was going to see if I could find a compounding pharmacy that was resonably priced to do same with the Aromasain in the lower dose. But that is issue another story. Got greddy trying to get everything reall cheap Totally messed up my trt meds for a bit.

Have you gotten your Hemocrit checked? I feel horrible when mine gets high. My doctor near even told me trt raises Hemocrit. Literally half way though giving blood and I feel like a new person. Your dose now might be low enough where it doesn't matter but at 200mg it probably spiked. That's dose I'm on and I every 8 weeks I have to donate or I'm sky high.

It takes time to really dial in ones trt. But once you get it it nailed in as what dose n times work. You'll feel a lot better.
 
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At IMT we have found splitting up your AI too much can cause you to drop your E too low, and concentrating it during times when your testosterone is rising can work much better.

Just my 2 cents :)
 
You should run 50mg of test every 3.5 days without an AI. Good chance you don't need one on that dose. Get labs and see how your numbers look.
 
Megatron28 said:
You should run 50mg of test every 3.5 days without an AI. Good chance you don't need one on that dose. Get labs and see how your numbers look.
Click to expand...

I see you recommend that a lot, just so you know many of our clients have tried this approach and did not like and actually brought back symptoms. One of which is a physician. The 50mg 2x a week works less often IMO than it works.

Just my 2 cents though, it does work well for some.
 
IMT staff said:
I see you recommend that a lot, just so you know many of our clients have tried this approach and did not like and actually brought back symptoms. One of which is a physician. The 50mg 2x a week works less often IMO than it works.

Just my 2 cents though, it does work well for some.
Click to expand...

Is it because in those cases the dosage was just simply a little on the low side?
 
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