Trt and weight to dosage ratio
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Jimstigator
New member
6 ft, 170, lean and muscular.
I am also curious for sure. 100mg a week EOD injections seems to be keeping me at about 900.
My initial treatment was 140mg a week EOD injections, 250iu HCG 2x week, and that had me <1500 and climbing.
-Jim
I am also curious for sure. 100mg a week EOD injections seems to be keeping me at about 900.
My initial treatment was 140mg a week EOD injections, 250iu HCG 2x week, and that had me <1500 and climbing.
-Jim
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JimiThing
Moderator
Adipose tissue is the largest source of aromatase storage s to a degree it is thought that the more adipose tissue the more aromatase but this isnt 100% true per se. There are many factors that dictate aromatse levels and amount of bodyfat could possibly even be a symptom of high levels of aromatse, not a cause. It all depends. Such a balancing act.
Alpin
New member
I hear you. What b.f. % would you say is significant to have a more sensitive reaction from over aromatization?
JimiThing
Moderator
I dont know that I can answer that. I do think you should be at a reasonable body fat to cycle but honestly the main reason for that isnt aromatization, it other health factors.
Alpin
New member
What else dictates aromatase levels?
Megatron28
Moderator
Madhaya
New member
>> Aromatase generation from adipose :reference <<
APOLLON <> As I am no Doctor, I'm only speaking from online research I've engaged, but as I have interpreted the data I've read, it seems fat cells GENERATE aromatase enzyme.
And then yes, are of course released into the bloodstream wherein they aromatize (aka, convert) testosterone molecules into estrogen.
REFERENCES:
"Abdominal fat in some circles has been referred to as an endocrine tumour for a good reason. Fat cells create aromatase enzyme that in turn further contributes to more build up of abdominal fat. Low testosterone allows the formation of abdominal fat, which then causes more aromatase enzyme formation thus further converting testosterone into estrogen." by Alexander Mostovoy, H.D., D.H.M.S. @ drmostovoy.com/Decline_of_Masculinity.htm
"Fat cells create aromatase enzyme and especially contribute to the buildup of abdominal fat. Low testosterone allows the formation of abdominal fat, which then causes more aromatase enzyme formation and thus even lower levels of testosterone and higher estrogen (by aromatizing testosterone into estrogen). It is especially important for overweight men to consider hormone modulation therapy." - dcnutrition.com/miscellaneous/detail.cfm?RecordNumber=475
"Aromatase is actually a complex of enzymes (not just one) that is largely produced by adipose (fat) tissue." By Ori Hofmekler in Maximum Muscle, Minimum Fat: The Secret Science Behind Physical Transformation
"As one ages, there is an increase in fat cells, which in turn causes an elevation in an enzyme called aromatase. This enzyme transforms testosterone to estrogen in the body. Secondarily, estrogen can indirectly cause an increase in a protein called sex-hormone-binding-globulin (SHBG), which binds to free testosterone and prevents its action. This protein will ultimately cause a decrease in testosterone." By Zina Kroner, D.O. @ drhoffman.com/article/hormone-replacement-for-andropause-2/
APOLLON <> As I am no Doctor, I'm only speaking from online research I've engaged, but as I have interpreted the data I've read, it seems fat cells GENERATE aromatase enzyme.
And then yes, are of course released into the bloodstream wherein they aromatize (aka, convert) testosterone molecules into estrogen.
REFERENCES:
"Abdominal fat in some circles has been referred to as an endocrine tumour for a good reason. Fat cells create aromatase enzyme that in turn further contributes to more build up of abdominal fat. Low testosterone allows the formation of abdominal fat, which then causes more aromatase enzyme formation thus further converting testosterone into estrogen." by Alexander Mostovoy, H.D., D.H.M.S. @ drmostovoy.com/Decline_of_Masculinity.htm
"Fat cells create aromatase enzyme and especially contribute to the buildup of abdominal fat. Low testosterone allows the formation of abdominal fat, which then causes more aromatase enzyme formation and thus even lower levels of testosterone and higher estrogen (by aromatizing testosterone into estrogen). It is especially important for overweight men to consider hormone modulation therapy." - dcnutrition.com/miscellaneous/detail.cfm?RecordNumber=475
"Aromatase is actually a complex of enzymes (not just one) that is largely produced by adipose (fat) tissue." By Ori Hofmekler in Maximum Muscle, Minimum Fat: The Secret Science Behind Physical Transformation
"As one ages, there is an increase in fat cells, which in turn causes an elevation in an enzyme called aromatase. This enzyme transforms testosterone to estrogen in the body. Secondarily, estrogen can indirectly cause an increase in a protein called sex-hormone-binding-globulin (SHBG), which binds to free testosterone and prevents its action. This protein will ultimately cause a decrease in testosterone." By Zina Kroner, D.O. @ drhoffman.com/article/hormone-replacement-for-andropause-2/
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LittleJohnny
6-Pack in Training
In the simplest explanation, bigger guys will require higher test doses because they have more blood. There's no getting around a simple mathematic equation that says, for example, someone who has 20% more blood requires 20% more test to reach the same measurement of X ng/dl. Obviously there are the slight variations that have already been mentioned here, but generally speaking, the more blood you have, the more test you need.
Virginian
New member
The article referenced by mrrippedzilla was hard to follow, but it said, "aMCR-T correlated positively with lean body mass..." What that means is that the body's removal rate for testosterone (aMCR-T) is proportional to lean body mass. Forgetting about obese people, that means that the more you weigh the faster you remove testosterone from your system.
