VERY VERY high E2, need advice please

L

lolque1658

New member
Ive been feeling like shit last 2-3 months and just got blood results. E2 is 261, normal range 7-42

Its weird because I'm cruising on 300 test for 10 weeks so far, before that i was on a 12 week Tren/mast/test cycle.

Im running 1mg adex ED for 8 days so far not sure what else i should do... When should I get my next blood test?
 
300mg is a high dosage to cruise at..

and runnning 1mg ed will only crash your estrogen and make you feel like shit all over again.. you need to slowly bring it down..

any rec drug use?
 
3J said:
300mg is a high dosage to cruise at..

and runnning 1mg ed will only crash your estrogen and make you feel like shit all over again.. you need to slowly bring it down..

any rec drug use?
Click to expand...

Why you ask 3j, about the rec drug use? Mary jane effect e2 drastically?
 
skinnypete said:
Why you ask 3j, about the rec drug use? Mary jane effect e2 drastically?
Click to expand...

it has said to have yes...


i have also dealt with clients in the past who abused the drug and had skyrocketed e2 levels.. they dropped dramatically when he stopped...


i dont know if it actually takes up e2 levels or if the test picks it up as estrogen.. i know its very similar in structure..
 
lolque1658 said:
Ive been feeling like shit last 2-3 months and just got blood results. E2 is 261, normal range 7-42

Its weird because I'm cruising on 300 test for 10 weeks so far, before that i was on a 12 week Tren/mast/test cycle.

Im running 1mg adex ED for 8 days so far not sure what else i should do... When should I get my next blood test?
Click to expand...

cruising at 300 that's high. Do you compete?
Is your adex bunk or is it a solid source?
 
skinnypete said:
Why you ask 3j, about the rec drug use? Mary jane effect e2 drastically?
Click to expand...

Rec drugs can definitely alter testosterone to estrogen ratio in favor of estrogen making a more suitable environment for gyno. From what I've seen on miss Mary, it's inconclusive but possible in humans. It's been shown to do so in mice but human studies the results have been mixed.
 
I get high estro on a 125/wk cruise, I'd suggest letro 2.5mg ed for a couple weeks. Do you have any lumps behind your nipples? if so, maybe a month of letro will get rid of them. Then when you are finished letro taper off of it to avoid estro rebound
 
3J said:
it has said to have yes...


i have also dealt with clients in the past who abused the drug and had skyrocketed e2 levels.. they dropped dramatically when he stopped...


i dont know if it actually takes up e2 levels or if the test picks it up as estrogen.. i know its very similar in structure..
Click to expand...

I have read conflicting reports, however I am interested in this... Maybe one of the cannabinoids present in MJ binds to AI's and renders them useless?
 
STAUNCHED427 said:
I have read conflicting reports, however I am interested in this... Maybe one of the cannabinoids present in MJ binds to AI's and renders them useless?
Click to expand...

It's got nothing to do with the AI as even ppl not on AI's will experience it. A study from the 80s shows a single of marijuana can impact testosterone, LH, and FSH levels negatively but this is only in the acute setting. Another study from the 90s tested chronic users and reported no significant differences in hormone levels implying the hormonal manipulation is an acute change and one the body gets used to after a while. There is no conclusive evidence tying marijuana to declining testosterone levels in otherwise healthy adult humans.

Another mechanism that's been theorized is that it increases estrogen levels and acts as estrogen at estrogen receptors. Again results are inconclusive in human studies.

Marijuana and its active component THC affect multi- ple endocrine systems. A suppressive effect is seen on the reproductive hormones, prolactin, growth hor- mone, and the thyroid axis, while the HPA axis is acti- vated. These effects are mediated through CB1 receptor. activation in the hypothalamus, which directly or indi- rectly modulates anterior pituitary function. Many of the responses observed, however, are lost with chronic administration, which is likely due to the development of tolerance. Studies in humans have had inconsistent results that may reflect differences in study design, the hormonal milieu (e.g., stage in menstrual cycle), or the development of tolerance. Long-term effects on the var- ious endocrine systems have not been clearly demon- strated, and clinical consequences, if present, are likely to be subtle.
Click to expand...
 
you both realize there are protocols out there, on other boards (many of them) outlining the 2.5 ed right? Can either of you tell me then the negative effects of high estrogen without googling, at what level they occur? I suppose you are both entitled to your opinions, mine is when estrogen is that high, to bring it down quickly. I will just use two reasons, the two that are most important to me and they are double the risk of stroke and increased risk of heart attack. Too much estrogen causes makes your blood thicker and I don't fuck with that. Not a random comment rather don't wait around to get back into healthy condition. I find it curious that neither of you have suggested any recourse, but are set that the one I have suggested is to be "never" undertaken. Spend some time reading up on it, the dangers for males, and then reconsider advising someone with 6x the upper range of estrogen to never take that much or that the suggestion is random which suggests no urgency for him. My advice to the op again is to get your estrogen down quickly.
 
olddawg said:
you both realize there are protocols out there, on other boards (many of them) outlining the 2.5 ed right?
Click to expand...

let me try comprehend that... so your saying just cuz "some idiots" that you have never met on other forums advise to take 2.5mg of letro every day, so without further research into the strength of letro and the negative sides of crushing the fvck out of your estrogen you strongly heed their advice and think this is the best possible dose to take letro and tell others they should do the same...?
 
kataklysum said:
let me try comprehend that... so your saying just cuz "some idiots" that you have never met on other forums advise to take 2.5mg of letro every day, so without further research into the strength of letro and the negative sides of crushing the fvck out of your estrogen you strongly heed their advice and think this is the best possible dose to take letro and tell others they should do the same...?
Click to expand...

I agree. I think arimidex the better option.
 
no, aggressive reduction of estrogen is needed not because it is on other boards, rather because of the risk of death. I was pointing out that there are many others who also disagree with your "never" statement and it would be easily searchable. Again, without a recommendation from yourself on anything relative to the op's question. Nice help. How about this, let's have a pissing match on who is right. Why don't you provide some research to support your point which at this point is doing nothing as unless I am mistaken, you have suggested no help to the op or raise any alarm for him other than you don't "like" what I have to say. You sir are contributing nothing toward this person's well being. If you want to argue please continue as I'm through. I've made my suggestion, as one should on a forum, I've supported it with some facts and will leave you with this:

We tested estrogen based on published data indicating that when estrogen levels are unbalanced, the risk of degenerative disease in aging men skyrockets.1-7 Of concern to us 14 years ago were reports showing that excess estrogen contributes to the development of atherosclerosis.8,9 Human clinical studies conducted more than a decade later confirmed our suspicions. Men with even slightly elevated estrogen levels doubled their risk of stroke and had far higher incidences of coronary artery disease.10-12 Our early observations also revealed that men presenting with benign prostate enlargement or prostate cancer had higher blood estrogen levels (and often low free testosterone blood levels).13-16 Subsequent clinical studies help confirm our early observations.17-21

so please, if you don't like the guy or if you don't like me, don't mess with his life. If you have anything to contribute other than "there is never a need for any male to take 2.5mg of letro. definitely not every day. thats crazy." to put words I my mouth to the effect of I'm saying to do this because other idiots do it is the crazy statement, look back, you even quoted me and I haven't said that. In addition my experience reducing lumps and combatting high estrogen at the 2.5 letro dosage has been successful. I'm sorry that you don't like it, however it has worked very well In my experience. So my argument is done with you sir. I'm sure you will have an intelligent recommendation for the op based in science but suggest you wait no longer to provide this to him. cheers

kataklysum said:
let me try comprehend that... so your saying just cuz "some idiots" that you have never met on other forums advise to take 2.5mg of letro every day, so without further research into the strength of letro and the negative sides of crushing the fvck out of your estrogen you strongly heed their advice and think this is the best possible dose to take letro and tell others they should do the same...?
Click to expand...
 
olddawg i think your getting a bit worked up over the subject. i totally agree with you high estrogen is bad, but so is no estrogen. maybe you got some underdosed letro who knows but when i convert raws into liquid letro 250mcg e3d is all that is needed. i know what 0.5mg e3d does to me so i couldnt imagine telling someone to take 2.5mg ed. thats over 15mg a week? that shit son is crazy...

if you do a google search on letro and see all the "i hate letro" threads youl realize every single one of them is taking a dose way to high and crushing their estrogen and giving them negative side effects and thats why everyone thinks letro "sucks" and if you have a look the doses their taking it is no where near your recommended 2.5mg dose that every guru recommends on these "other forums"...

2.5mg of letro every day is never a good idea. im not sayin, im just sayin...
 
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