last info before its here!!!!!!!
prepared by HUCK
Many have touted Glutamine supplementation as one of
the missing pieces of the hypertrophic/anti-catabolic puzzle for
intensely
training athletes.It has been shown to be beneficial when dieting or training frequently and very
intensely.Up
until now,some of the drawbacks to oral glutamine supplementation was
the absorbability factors.The L-form just required mass amounts to pass
the gut membrane and be taken up to target tissues.As a result,much was
wasted.But now,with the advent of peptide bonded forms of
glutamine,this
problem has been efficiently overridden.The peptide glutamic substrates
are taken up much more easily,and as a result,much higher plasma
concentrations
are achieved,with much less required to achieve this end
result.
G-plenish Glutamine peptides is a form of Glutamine unlike any other
it is a matrix of peptides that including all 8 essential amino acids that we need bound to glutamine.A natural source of glutamine, derived from 100% protein, peptides have better absorption characteristics. Glutamine peptides contain additional peptide fractions not available in pure L-glutamine products making it stable in a solution because it contains bound glutamine. It has a higher solubility and heat stability over a wide temperature range. This allows the peptide bonded glutamine to be acid and heat stable so cooking and/or acidic beverages will not destroy the glutamine.
Now,with
this in mind,one may still question,"Why glutamine?What will it do for
me,the athlete?"
Glutamine is the most abundant occuring amino acid present in the
entire
body,comprising about 75% of the muscle cell amino acid pool.
During stress,the body's requirement for glutamine often appears to
excede
our ability to produce sufficient amounts to reinstate cell pool
homeostasis.Stress
causes increased amounts of glutamine to release from muscle,and it
becomes
difficult to restore,presumably as a result of disturbances of the
Na+electrochemical
gradient across the cell membrane.Liver and spleen uptake of glutamine
is also increased during these stressful times,further displacing the
content present in muscle.Low plasma concentrations of glutamine
reflect
reduced stores in muscle tissue.Feeding extra amounts of readily
available/easily
absorbed peptide bound glutamine during these periods would be a wise idea to
counterattack these catabolic mechanisms and sustain the muscle amino
pool content.
On a cellular level,let's take a look at why glutamine is such a
worthwhile
substrate-Some of its proven benefits:
*It attenuates glutathione depletion( Glutathione is the most important
endogenous scavenger system/anti-oxidant in the entire body).
Glutathione depletion is often pronounced after bouts of
stress,including
events of high intensity excercise such as we subject ourselves to
during
heavy training.
*Glutamine has been shown to stimulate/activate protein synthesis and
inhibit turnover(degradation).It has been shown to enhance/sustain
nitrogen
homeostasis under periods of stress.
*Glutamine modulates lymphocyte(immune cell)activation,by
proliferating(increasing
population)of T-Cell numbers which in turn increases immune system
response.Parenteral
administration in hospital patients under stress has been found to
greatly
decrease the instance of bacterial infections.
Glutamine Peptides which our bound to other protiens incuding all 8 essential amino acids help the rest of us achieve this benifit
*Stimulates hepatic(liver)glycogen synthesis.
*Glutamine has also been shown to enhance stress-induced heat shock
protein(HSP)___expression.HSP's
provide protection of cellular injury.
*Lastly, glutamine peptides have the antioxidant action similar to 3-5 servings of fruit or vegetables based on ORAC (oxygen radical absorbance capacity) for vitamins C, E, and beta-carotene. Glutamine peptides offer 300 times more ORAC antioxidant equivalents as compared to free glutamine.
SOURCE ORAC INTAKES
Vitamin E (500mg) 116
Vitamin C (500mg) 2830
3-5 servings of fruits and vegetables 1950
B-carotene (250mg) 300
Free amino acid glutamine (5-7g) 3.5-5.4
Protein hydrolysate (10-15g) 1100-1650
Oral administration of glutamine,particularly in peptide-
chained form very well may improve nitrogen economy/retention,improve
repair/recovery of damaged muscle tissue,and diminish the the incidence
of free radicals/bacterial forms present in those who are placing
stress
on their systems through the routines of high intensity training.
its all in the attention to detail.
