What sensitive E2 number do you guys aim for?

On the sensitive test, I've gotten a 17, and a 21. I haven't noticed a difference, and I've felt really good. At 10, I don't feel so good.
 
I only go by regular assay. Sensitive is not available at any lab I go to. Nothing more than 36 ish I'd say...
Nothing less than 20 but keep in mind you aromatize differently on TRT vs when you were natty.
While off any TRT I've lowered estradiol to 14 and below and never felt the symptoms I did when lowering to that same level on TRT....
 
My E2(S) seems to stay below 10 while my total estradiol is around 13-14 and I feel fine at those levels. I'm using a topical for TRT so my DHT is typically high. High DHT tends to lower estrogen.
 
My E2(S) seems to stay below 10 while my total estradiol is around 13-14 and I feel fine at those levels. I'm using a topical for TRT so my DHT is typically high. High DHT tends to lower estrogen.

Damn thats low.

I shoot for 20-30 sensitive. It was tanked for a month a while back and holy shit was that bad. It came back at <3 on three consecutive tests. Minus gyno if you are sensitive to it, I would much rather be a notch too high than low.

-Jim
 
I wouldn't mind it if mine was a bit higher but that's just where is seems to stay. I'm sure that topical TRT is a big part of the reason it's that low. What's really weird is that even with my E at these levels, I battled with my pre-existing gyno for a while. I assume it had something to do with prolactin but letro took care of the problem.
 
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Damn thats low.

I shoot for 20-30 sensitive. It was tanked for a month a while back and holy shit was that bad. It came back at <3 on three consecutive tests. Minus gyno if you are sensitive to it, I would much rather be a notch too high than low.

-Jim
When first hoping on TRT I noticed some pretty bad anxiety including Adex from the get go. I was dosing 0.25 mg EOD...Man was that a mistake.
a tad high is way better than too low.
 
I wouldn't mind it if mine was a bit higher but that's just where is seems to stay. I'm sure that topical TRT is a big part of the reason it's that low. What's really weird is that even with my E at these levels, I battled with my pre-existing gyno for a while. I assume it had something to do with prolactin but letro took care of the problem.

Interesting! I always thought the creams/gel caused more conversion to estrogen and people struggled with high E2 issues. So you are that low with no adex? Any other supps with small anti-e effects such as DIM or zinc?

When first hoping on TRT I noticed some pretty bad anxiety including Adex from the get go. I was dosing 0.25 mg EOD...Man was that a mistake.
a tad high is way better than too low.

When I was on long term low dose Nolva, I needed .25mg ADEX five days a week to keep E2 under control. Then, I got off Nolva and switched to TRT (test cyp), which put me at the exact same TT as Nolva but almost immediately that same ADEX dose crashed my E2 to basically zero.

I had heard SERMS can reduce the effectiveness of AIs - confirmed with first hand experience. OR - another theory is high levels of LH can produce some form of estrogen in the testes thats immune to AIs. This is all bro-science from another forum, but from what I gather, its why some people lose control of E when using high levels of HCG as the method its creating estrogen via the testes and not T->E conversion makes it somewhat resistant to AIs.

For me...
Low dose nolva + ADEX 1.25mg a week = 900 TT 30 E2
100mg Test Cyp w/ no ADEX = 900 TT 18 E2


-Jim
 
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When I was on long term low dose Nolva, I needed .25mg ADEX five days a week to keep E2 under control. Then, I got off Nolva and switched to TRT (test cyp), which put me at the exact same TT as Nolva but almost immediately that same ADEX dose crashed my E2 to basically zero.

I had heard SERMS can reduce the effectiveness of AIs - confirmed with first hand experience. OR - another theory is high levels of LH can produce some form of estrogen in the testes thats immune to AIs. This is all bro-science from another forum, but from what I gather, its why some people lose control of E when using high levels of HCG as the method its creating estrogen via the testes and not T->E conversion makes it somewhat resistant to AIs.

For me...
Low dose nolva + ADEX 1.25mg a week = 900 TT 30 E2
100mg Test Cyp w/ no ADEX = 900 TT 18 E2


-Jim

When you were only running Nolva your HPTA feedback loop was still open (LH/FSH ---> Testosterone --> Estradiol). When you went on testosterone the feedback loop was closed. That is why you had to change your AI dosage.
 
I hope medical science makes a Testosterone that does not aromatize...something like a built in a.i. in the compound...
boy will that be awesome. ..
maybe we won't see it in our lifetime.
 
One possible approach could be to suppress aromatization completely and combine exogenous estradiol with test in the proper ratio.

Put them all in a single injectable.
 
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Interesting! I always thought the creams/gel caused more conversion to estrogen and people struggled with high E2 issues. So you are that low with no adex? Any other supps with small anti-e effects such as DIM or zinc?

Creams and gels applied to the skin have a high conversion to DHT. DHT is the bodies own natural AI. Those applied to the scrotum can convert at 3x higher than other areas of the body. I have confirmed this via blood testing. Even application to my inner arms keeps my DHT above normal levels.
 
One possible approach could be to suppress aromatization completely and combine exogenous estradiol with test in the proper ratio.

Put them all in a single injectable.

that is a very interesting idea. just take a ton of letro and demolish your e2 and inject synthetic.....i'm sure they have the technology and resources to do that easily.
 
that is a very interesting idea. just take a ton of letro and demolish your e2 and inject synthetic.....i'm sure they have the technology and resources to do that easily.

A compounding pharmacy should totally be able to produce this on request.
 
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