Anti-aromataze vs. blocker

[Ace]

If proviron, adex/ldex, clomid and femara among others are anti aromotase anti-Es that downregulate or fully block estrogen from ever being produced, why would we still use anti-Es such as nolva or exemastane?

Wouldn't we all like to stop estrogen at the source instead of "fixing" it while it has already been produced?

One argument that I could possibly see is to stack nolva with an anti-aromotaze anti-E because of nolva's positive effects on your lipid profile and cholesterol, but other than that, I see none.

 

[Jawbone]

I have been told by Hormone Replacement Therapy (HRT) docs that SERMS have stimulatory effect on the pituitary, AIs do not.

 

[Eze]

Usually nolva is kept on hand just in case. If you start to feel signs of gyno, that's when you start the nolvadex.

Sometimes an Anti-aromataze isn't enough, and that's when Nolva comes in handy.

 

[StoneColdNTO]

If proviron, adex/ldex, clomid and femara among others are anti aromotase anti-Es that downregulate or fully block estrogen from ever being produced, why would we still use anti-Es such as nolva or exemastane?

Wouldn't we all like to stop estrogen at the source instead of "fixing" it while it has already been produced?

One argument that I could possibly see is to stack nolva with an anti-aromotaze anti-E because of nolva's positive effects on your lipid profile and cholesterol, but other than that, I see none.

The true anti-aromatases are Arimidex, Letrozole, and Aromasin. Proviron would be a weak one, but not Clomid, it is a SERM, like Nolvadex.

Now, even with an anti-aromatase, some aromatization still occurs, and this may affect individuals sensitive to estrigen, hence the need of Nolvadex in gyno prevention.

 

[Dizzy]

Clomid is a SERM. Proviron is an actual steroid that downregulates estrogen receptors. Femara and Arimidex are aromatase inhibitors. Aromasin is an irreversible, steroidal aromatase inactivator. Aromatase inhibitors transiently bind to aromatase, whereas aromatase inactivators permanently bind to the enzyme.

Each one is used for different reasons:

Clomid - Mainly post cycle as most know. Can be used to fight gyno, but is a rather weak anti-estrogen.

Nolvadex - Best drug to prevent gyno or rid of gyno symptoms IMO. Also can be used post cycle.

Proviron - Can be used as an anti-e, but again, is rather weak. Proviron is mainly used in keeping libido alive during and post cycle.

Arimidex and Femara - Best suited for combating water retention.

Aromasin - I really don't see much need for bodybuilders to use this drug. Why permanently rid of estrogen? Estrogen has positive effects, and negative effects can occur without it, like bad cholesterol. I've heard femara is much better at fighting water retention than aromasin anyway.

I use Femara (water retention), Clomid (PCT), and Nolva (gyno prevention, PCT).

 

[Ace]

OK, thanks for the information guys. That answered my question.

 

[DADAWG]

also remember you do NOT want to eliminate estrogen just keep it under control

 

[Ace]

also remember you do NOT want to eliminate estrogen just keep it under control

I gathered that by my research. Thanks bro!