Actually there (
potentially) is. Problem is, no ER is going to know about it lol. Might be handy to remember just in case though
![Stick out tongue :p :p](https://cdn.jsdelivr.net/joypixels/assets/8.0/png/unicode/64/1f61b.png)
I think the danger with ER is also that they attempt to flush it out of you with fluids... unknowingly causing further electrolyte depletion. It's a tough one to treat for sure. This is exactly why it's so damn important to know the drug inside & out and to be as conservative and careful as possible.
Here's a post from Conciliator on the subject:
Dinitrophenol-induced hyperthermia has been resolved with dantrolene administration. Let me quote from this paper:
http://www.ncbi.nlm.nih.gov/entrez/q...0&cmd=Retrieve
We previously reported a patient with dinitrophenolinduced
hyperthermia, which improved following dantrolene
administration (2). The patient was a thirty year-old male who
presented to an emergency department with diaphoresis, beet
red skin, and yellow sclera. He initially denied ingestion of any
toxic substance, but it was subsequently learned that he was
taking dinitophenol for weight loss and body building. While
in the emergency department, his mental status deteriorated
and he was intubated. His body temperature rose to 108 ?F
(42.2?C). Cooling blankets, fans, and tepid water soaks
decreased his temperature to 104?F (40?). However, within 20
minutes of the administration of dantrolene, his body temperature
decreased to 100.8?F (38.2?C). Dantrolene was repeatedly
administered over the next 12 hours to maintain body temperature
below 100.4?F (38?C). Over the next 12 days he developed
rhabdomyolysis and renal failure which resolved. He was
extubated on day twelve. He had no known permanent
sequelae from the overdose and was discharged from the
hospital.
Studies have not found a benefit from administration of
dantrolene to treat hyperthermia caused by heatstroke, cocaine,
or amphetamines. However the underlying etiology of the
hyperthermia may determine if dantrolene administration will
decrease temperature. Dinitrophenol uncouples oxidative phosphorylation,
causes release of calcium from mitochondrial
stores and prevents calcium re-uptake (3). This leads to free
intracellular calcium and causes muscle contraction and
hyperthermia. Dantrolene inhibits calcium release from the
sarcoplasmic reticulum which reduces intracellular calcium.
The resulting muscle relaxation allows heat dissipation (4).
There is little risk to dantrolene administration. Since dantrolene
may be effective in reducing hyperthermia caused by
agents that inhibit oxidative phosphorylation, early administration
may improve outcome.