is this true

rippedfuel

New member
I suppose that the reason most people avoid using Deca and Tren together is that they are both Progestins (they stimulate the progestin receptor). Progesterone has a relative binding affinity (to the Progesterone Receptor) of 100. Deca has an affinity of 20 and Tren has an affinity of 60. That means deca stimulates the progesterone receptor 20% as much as pure progesterone, while tren does it 60% as much.
 
I don't know anything about those numbers, but if progestin receptors are anything like, for example, estrogen receptors, then not all progestin receptors are the same.

When it comes down to it, different people respond differently. You certainly wouldn't want to try deca and tren at the same time if you hadn't tried each of them seperately first. But that goes along with our usual advice. Never introduce more than one new hormone in any cycle.
 
rippedfuel said:
That means deca stimulates the progesterone receptor 20% as much as pure progesterone, while tren does it 60% as much.


Yes, that is correct. This study pretty much explains receptor binding (I don't think it is on line but you could try digging for it). But those are the numbers that are often quoted.

Ojasoo T, Raynaud JP. Unique steroid congeners for receptor studies. Cancer Res. 1978 Nov;38(11 Pt 2):4186-98.
 
so in essence, tren cause progestin gyno at 40% higher rate than deca

(deca being 20% and tren being 60%)

I would have thought the other way around.
Good to know...................thnx
 
rippedfuel said:
so in essence, tren cause progestin gyno at 40% higher rate than deca

Nope, that's not quite what it means. Basically it just means that it is going to react with the receptor at 60% of the rate of prog. itself (or 20% in the case of deca). This does not mean that it will cause gyno at a 40% higher rate than deca. It's a bit more complicated than that.
 
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