Results after 6 weeks on testosterone replacement therapy (TRT) (100mg TestC E7D and 500iu's Human Chorionic Gonadotropin (HCG) EOD)

Waterpolo820

New member
Results after 6 weeks on TRT (100mg TestC E7D and 500iu's HCG EOD)

Hey everyone
So this is how I'm looking after 6 weeks of my new regimen of testosterone replacement therapy (TRT) (after trying Clomid and Adex 1md ED)

My current Regimen: 100mg TestC E7D(IM) and 500iu's Human Chorionic Gonadotropin (HCG) EOD (SQ)

Trough Total Test......778 (400-1197)
Peak Total Test..... 1325 (400-1197)
LH ........ <.2 (1.7-4.2)
FSH ........ <.2 (1.9-4.7)
E2 (taken at trough) ...... 49.4 (7.2-47.2)

Don't clearly remember if my Doc had Free test on there and they forgot to test for it or if he didn't write that down.

Overall I'm feeling better the first two days after pinning but nothing spectacular, which I'm taking that as the E2 levels as being the reason for that
I have some Adex laying around so I might start a quarter tablet E3D and I'm thinking about cutting back on the Human Chorionic Gonadotropin (HCG) since it's clearly not doing anything for keeping my levels up (using Human Chorionic Gonadotropin (HCG) for the reason of having kids later in life, I'm only 22)

My next appt with my doc is in a month because he is so busy and I waited so long to make an appointment but I can get lab work whenever I want so I'm probably going to try dialing in my levels myself before the appointment


Question: Is the Human Chorionic Gonadotropin (HCG) causing the E2 levels being so high? If I cut back on that will it take it back to an optimal range (20-30) or will I need Adex on top of cutting back on the HCG??
Thinking about cutting the dosage of Human Chorionic Gonadotropin (HCG) to 250iu EOD, just for the point of atrophy... I already cryo'd a couple samples prior to starting testosterone replacement therapy (TRT) on recommendation from the Doc
 
Hey everyone
So this is how I'm looking after 6 weeks of my new regimen of testosterone replacement therapy (TRT) (after trying Clomid and Adex 1md ED)

My current Regimen: 100mg TestC E7D(IM) and 500iu's Human Chorionic Gonadotropin (HCG) EOD (SQ)

Trough Total Test......778 (400-1197)
Peak Total Test..... 1325 (400-1197)
LH ........ <.2 (1.7-4.2)
FSH ........ <.2 (1.9-4.7)
E2 (taken at trough) ...... 49.4 (7.2-47.2)

Don't clearly remember if my Doc had Free test on there and they forgot to test for it or if he didn't write that down.

Overall I'm feeling better the first two days after pinning but nothing spectacular, which I'm taking that as the E2 levels as being the reason for that
I have some Adex laying around so I might start a quarter tablet E3D and I'm thinking about cutting back on the Human Chorionic Gonadotropin (HCG) since it's clearly not doing anything for keeping my levels up (using Human Chorionic Gonadotropin (HCG) for the reason of having kids later in life, I'm only 22)

My next appt with my doc is in a month because he is so busy and I waited so long to make an appointment but I can get lab work whenever I want so I'm probably going to try dialing in my levels myself before the appointment


Question: Is the Human Chorionic Gonadotropin (HCG) causing the E2 levels being so high? If I cut back on that will it take it back to an optimal range (20-30) or will I need Adex on top of cutting back on the HCG??
Thinking about cutting the dosage of Human Chorionic Gonadotropin (HCG) to 250iu EOD, just for the point of atrophy... I already cryo'd a couple samples prior to starting testosterone replacement therapy (TRT) on recommendation from the Doc

First thing you should do is start injecting 50mg every 3.5 days instead of 100mg every 7 days. This will lower your E2 and keep you T levels more even. Going fro. 800-1300 is a big swing.

Try it for a month and then re-run labs to see how you are doing.

Good luck.
 
Not sure what you mean by Human Chorionic Gonadotropin (HCG) not keeping your levels up... Human Chorionic Gonadotropin (HCG) will mimic the actions of LH and FSH but will not raise them. The Human Chorionic Gonadotropin (HCG) may be contributing to your T (and E2) levels. That said, 500 units EOD is more than most use.
 
Hey everyone
So this is how I'm looking after 6 weeks of my new regimen of testosterone replacement therapy (TRT) (after trying Clomid and Adex 1md ED)

My current Regimen: 100mg TestC E7D(IM) and 500iu's Human Chorionic Gonadotropin (HCG) EOD (SQ)

Trough Total Test......778 (400-1197)
Peak Total Test..... 1325 (400-1197)
LH ........ <.2 (1.7-4.2)
FSH ........ <.2 (1.9-4.7)
E2 (taken at trough) ...... 49.4 (7.2-47.2)

Don't clearly remember if my Doc had Free test on there and they forgot to test for it or if he didn't write that down.

Overall I'm feeling better the first two days after pinning but nothing spectacular, which I'm taking that as the E2 levels as being the reason for that
I have some Adex laying around so I might start a quarter tablet E3D and I'm thinking about cutting back on the Human Chorionic Gonadotropin (HCG) since it's clearly not doing anything for keeping my levels up (using Human Chorionic Gonadotropin (HCG) for the reason of having kids later in life, I'm only 22)

My next appt with my doc is in a month because he is so busy and I waited so long to make an appointment but I can get lab work whenever I want so I'm probably going to try dialing in my levels myself before the appointment


Question: Is the Human Chorionic Gonadotropin (HCG) causing the E2 levels being so high? If I cut back on that will it take it back to an optimal range (20-30) or will I need Adex on top of cutting back on the HCG??
Thinking about cutting the dosage of Human Chorionic Gonadotropin (HCG) to 250iu EOD, just for the point of atrophy... I already cryo'd a couple samples prior to starting testosterone replacement therapy (TRT) on recommendation from the Doc

My estradiol level was outside the upper limit when I started Hormone Replacement Therapy (HRT) last month. My Dr. will not prescribe me Human Chorionic Gonadotropin (HCG) (even though I used it in the past with success). He said one of the reasons he will not prescribe it to me is due to my sensitivity to estrogen.

I would try the following (it was my protocol the first time with HRT): take 250 to 350 iu of Human Chorionic Gonadotropin (HCG) the day prior to weekly injection of testosterone, take injection of testosteone, then complete your weekly protocol by taking .5 mg of arimidex the day following weekly injection of testosterone.

You may also want to consider cutting your testosterone injection dosage in-half and injected twice a week to avoid aromatization issues. If you do so, only take .25 mg of arimidex initially. Too low of an estrogen level is not healthy either. Just my .02.
 
Last edited:
What I don't get is should we take Adex EOD or E3D ?
Sources out there are saying 48 hour half life and 72 hour half life....depends where you look.
Who's right?
When was "Trough Total Test" measured...how many days from shot?
In regards to the 1300 T.T. level....please tell us how many days from shot that was for you...
 
What I don't get is should we take Adex EOD or E3D ?
Sources out there are saying 48 hour half life and 72 hour half life....depends where you look.
Who's right?
When was "Trough Total Test" measured...how many days from shot?
In regards to the 1300 T.T. level....please tell us how many days from shot that was for you...

I've struggled with the dosing of Arimidex EOD or E3D as you mentioned as well. I've also seen multiple references to half-life as you referenced. I finally came to the conclusion that each person metabolizes a medication differently and with Arimidex your overall sensitivity to estradiol has to be considered.

For reference sake, my current Dr. prescribed me .5 mg of Arimidex per day. I told him that was a hefty dosage, but he said my excess abdominal fat was the basis for prescribing so much. I'm probably in the 30% BF to 35% BF range right now.

By the way, I don't take the .5 mg of Arimidex per day that he prescribed. I now take .25 mg ED or .5 mg EOD.
 
First thing you should do is start injecting 50mg every 3.5 days instead of 100mg every 7 days. This will lower your E2 and keep you T levels more even. Going fro. 800-1300 is a big swing.

Try it for a month and then re-run labs to see how you are doing.

Good luck.

Megatron, I just wanna get some clarification on this. You are saying he should split the dose but should he stop taking the A dex or continue taking the A- dex?
 
Megatron, I just wanna get some clarification on this. You are saying he should split the dose but should he stop taking the A dex or continue taking the A- dex?


He currently is not taking an Aromatase inhibitor (AI). So I was suggesting that he try splitting his test dose into two injections per week first. I would not add an Aromatase inhibitor (AI) at this point. If splitting the test dose doesn't get his E2 in line then I would look at adding an AI.
 
What I don't get is should we take Adex EOD or E3D ?
Sources out there are saying 48 hour half life and 72 hour half life....depends where you look.
Who's right?
When was "Trough Total Test" measured...how many days from shot?
In regards to the 1300 T.T. level....please tell us how many days from shot that was for you...

My 1300 TT Peak test was taken 1 day after my injection

and my trough test was taken the day before my injection

At the time I was injection E7D
 
He currently is not taking an Aromatase inhibitor (AI). So I was suggesting that he try splitting his test dose into two injections per week first. I would not add an Aromatase inhibitor (AI) at this point. If splitting the test dose doesn't get his E2 in line then I would look at adding an AI.

Megatron, thanks like always for the responses
I've started splitting the injections to E3.5D this week; going to let it balance out and get retested in 2-3 weeks.
Is that sufficient time to let my body adjust to the new protocol??
 
Megatron, thanks like always for the responses
I've started splitting the injections to E3.5D this week; going to let it balance out and get retested in 2-3 weeks.
Is that sufficient time to let my body adjust to the new protocol??

I personally like to give it a month before I run labs after making a change. I would wait 3 weeks minimum. But that just me.
 
As megatron said, splitting the injection into two 50mgs per week should drop your estrogen quite a bit and put you in range.
I don't see you needing an Aromatase inhibitor (AI) as long as you split your dosage.
Remember this is not a sensitive estrogen panel you're having done so being 30-40 is a good thing as long as your test levels are around 8-1000 and of course you feel good.
 
As megatron said, splitting the injection into two 50mgs per week should drop your estrogen quite a bit and put you in range.
I don't see you needing an Aromatase inhibitor (AI) as long as you split your dosage.
Remember this is not a sensitive estrogen panel you're having done so being 30-40 is a good thing as long as your test levels are around 8-1000 and of course you feel good.

I guess that's where I am a little frustrated about, I don't feel like I am that much better. Still waking up tired not being able to sleep through the whole night, brain fog and all the other classic symptoms are still there.
From reading everyone else's posts, if I'm in the 1300's I should feel unstoppable, right? haha
 
I guess that's where I am a little frustrated about, I don't feel like I am that much better. Still waking up tired not being able to sleep through the whole night, brain fog and all the other classic symptoms are still there.
From reading everyone else's posts, if I'm in the 1300's I should feel unstoppable, right? haha

only if you E2 is in check.. Question: How did you feel the first couple of weeks? Reason I ask is because when I was taking 200/wk I felt great for about 6 weeks then I started to feel like crap again. Had bloods done on my day of injection and my E2 came back in the 50's and my test was over 1400. Keep in mind this was 7 days after my last injection. I can't imagine what my peak numbers are. I've since cut back to 180mg. I eventually want to get down to 100-120/week. Good luck brother..
 
only if you E2 is in check.. Question: How did you feel the first couple of weeks? Reason I ask is because when I was taking 200/wk I felt great for about 6 weeks then I started to feel like crap again. Had bloods done on my day of injection and my E2 came back in the 50's and my test was over 1400. Keep in mind this was 7 days after my last injection. I can't imagine what my peak numbers are. I've since cut back to 180mg. I eventually want to get down to 100-120/week. Good luck brother..

First four weeks I felt absolutely no difference, about week 5 I began feeling slightly better on day 1 and two after my injection then back to how I felt before starting day 3. This is now week 7 and that difference that I use to feel on week 5&6 is now completely gone and I'm back to my pre-week 5 overall feel.

I didn't get my E2 tested on my peak, only on my trough, and I was sitting at 49.2; so I can only imagine that my peak is even higher out of the limit.
I started started splitting my dosage this week to 50mg 2x week and I'm going to see where that takes me.
 
That's a lot of Human Chorionic Gonadotropin (HCG) most people only use 250iu any reason for this? I myself am attempting a restart and I'm only on 500iu e3d
 
That's a lot of Human Chorionic Gonadotropin (HCG) most people only use 250iu any reason for this? I myself am attempting a restart and I'm only on 500iu e3d

Doctor's order - I'm only 22 and want to have kids in the future so I guess he's upping the dosage to make sure of that(?) I don't really have a specific reason for the high dosage other than that
 
Doctor's order - I'm only 22 and want to have kids in the future so I guess he's upping the dosage to make sure of that(?) I don't really have a specific reason for the high dosage other than that

You might want to do your own homework on Human Chorionic Gonadotropin (HCG) here on this forum. I don't use it, but my understanding is that using that much that frequently can be counterproductive. There are a lot of posts on the topic of Human Chorionic Gonadotropin (HCG) that you can go back and read.

Remember, many docs don't know a tremendous amount about testosterone replacement therapy (TRT). It won't take much studying for you to know more than many docs know.
 
Back
Top