Trenbolone, a practical application by heavyiron

heavyiron

Community Veteran
Trenbolone Acetate may be used for cutting, bulking or re-comping. This steroid is very versatile. But out of the three, Trenbolone seems best suited for re-comping. Body re-composition is when you lose body fat and gain muscle mass. It’s not just cutting fat but cutting fat AND adding muscle. If you have been bodybuilding for any period of time you understand how difficult this can be. In fact, re-comping becomes harder and harder the longer you body build. Eventually you hit a wall. This is when we may add Trenbolone to keep gains rolling.

History

Trenbolone is available in a variety of esters that prolong the release time of this hormone. In 1967 Trenbolone was well studied attached to the long acting undecanoate ester. This ester is similar in action to the French Parabolan brand, also called Hexabolan due to the hexahydrobenzylcarbonate ester. Parabolan was sold for human consumption by Negma Laboratories therefore Trenbolone was a legitimate medicine approved for human use at one time. Trenbolone Acetate was the ester of choice used in the early 1970’s in veterinary medicine. Trenbolone Acetate was marketed at this time in England under the brand name Finajet and as Finaject in France. Trenbolone acetate in the form of Finaplix pellets has been widely used all over the world to add weight and improve feed efficiency in cattle.

Cycling for men

Setting up a cycle with Trenbolone depends on many things such as goals, experience level, side effects experienced and threshold for risk. I personally have found that Trenbolone stacked in a specific dose with Testosterone and timed properly can illicit terrific results on a re-comp while minimizing side effects. The following are some sample cycles using Trenbolone Acetate on a re-comp.

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*This cycle is for newer users of Trenbolone Acetate*

Week 1-8 500mg Testosterone C or E
Week 9-12 750mg Testosterone / 350mg Tren Ace
Week 13 350mg Tren Ace

Tren Ace (100mg eod) is added at week 9 just about the time gains begin to diminish in a standard cycle. This timing is critical to "push" gains so do not alter the timing. The Tren Ace is ran for a short but effective 5 weeks. This will give a first time user some experience with the compound to assess side effects. Running the Tren the 13th week will keep gains rolling while the Testosterone E or C ester is clearing. Testosterone Propionate may be run throughout as well.

*This cycle is for experienced users going into a 16 week prep*

Week 1-6 500mg Test E
Week 7 750mg TE
Week 8 1 gram TE
Week 9 1 gram TE / 350mg Tren Ace
Week 10 1,250mg TE / 350mg Tren Ace
Week 11 1,250mg TE / 350mg Tren Ace
Week 12 1,500mg TE / 350mg Tren Ace
Week 13 525mg Tren Ace / 525mg Test Prop
Week 14 525mg Tren Ace / 525mg Test Prop / 100mg Winstrol tabs daily
Week 15 525mg Tren Ace / 100mg Winstrol tabs daily
Week 16 100mg Winstrol tabs daily

Tren Ace (100mg eod) is added at week 9 just about the time gains begin to diminish in a standard cycle. This timing is critical to "push" gains so do not alter the timing. Notice the Tren and Test Prop extend 2 weeks past the higher dose of Testosterone. This is purposeful to keep gains rolling while the higher dose T Enanthate is clearing. Basically gains should continue through week 14 with this setup.

Ancillaries and post cycle therapy

Cabergoline will lower prolactin and using an aromatase inhibitor alongside it will control E2 from the Testosterone during the cycle. I personally prefer Pramipexole over Cabergoline since Pramipexole has the ability to raise GH and still works well to lower prolactin.

I would run HCG at least the last 3-4 weeks on cycle and while the meds are clearing. Clomid is a great recovery drug at 50-100mg daily for 4-6 weeks for post cycle therapy (pct). Some guys need an Aromatase inhibitor (AI) after the Clomid but only labs can confirm this. If the individual is on hormone replacement therapy that therapy may be resumed immediately post cycle rather than using the above PCT.

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Ladies and Trenbolone

Trenbolone is virilizing in women so extreme caution must be used when administering Trenbolone to females. Virilization in a woman can manifest as clitoral enlargement, increased muscle strength, acne, hirsutism, frontal hair thinning, deepening of the voice, and menstrual disruption. Depending on the female’s threshold for risk, 30mg of Trenbolone Acetate weekly is where I would advise a lady to start. (10mg mon, wed, fri.) More adventuresome females may take 90mg Tren Ace weekly but I would not advise that on a first run. I recommend an insulin syringe to get very accurate dosing and lower the risk of scar tissue.

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Trenbolone for androgen replacement in men

In January 2011 Trenbolone Enanthate was studied as a possible alternative for Testosterone replacement therapy in the hopes that Trenbolone would not increase prostrate mass or cause adverse hemoglobin elevations and that it would prevent bone and muscle loss. The following is a direct quote from the abstract.

“In summary, low-dose administration of the non-5a-reducible androgen TREN maintains prostate mass and hemoglobin concentrations near the level of shams while producing potent myotrophic actions in skeletal muscle and partial protection against orchiectomy-induced bone loss and visceral fat accumulation. Our findings indicate that TREN has advantages over supraphysiological testosterone and supports the need for future preclinical studies examining the viability of TREN as an option for androgen replacement therapy.”

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Trenbolone Acetate is a steroid I have had a love hate relationship with. I love Tren’s powerful positive effects but hate the equally powerful side effects. Over the years I have experimented with various methods of using Trenbolone to its full advantage but at the same time minimizing the side effects. The side effects that users report range from increased aggression, insomnia, profuse sweating, “Tren cough” and reduced libido as well as a host of other sides that are common with androgen's.

Trenbolone is quite powerful especially when used in certain ways. In fact, Trenbolone is 3-5 times more anabolic and androgenic than Testosterone. Trenbolone binds to androgen receptors (ARs) with approximately three times the affinity of testosterone and has been shown to augment skeletal muscle mass and bone growth and reduce adiposity! Tren is one potent weapon in the bodybuilder’s arsenal. Therefore, trying to figure out a way to maximize Trenbolones amazing potential while minimizing its side effects has been a pursuit of mine. Obviously, reducing the dosage is a way to reduce side effects since many times side effects are dose dependent. Some users report that small, every day injections reduce side effects and this can easily be done with an insulin syringe in a lean muscle group. Stacking with complimentary steroids such as Testosterone maximizes Trenbolones potential and also reduces side effects such as loss of libido. I'm convinced there's almost no other traditional injectable stack that's as potent and versatile as Testosterone and Trenbolone. It's a simple stack with enormous potential to harden muscle, promote fat loss and add raw strength. Since Trenbolone is so anabolic it's a great muscle builder as well. I prefer dosing Testosterone at least two times higher than the Trenbolone dose however when entering a contest prep I prefer the opposite. I recommend either a replacement dose of Testosterone with Tren or no Testosterone at all in the final weeks of prep to illicit a dry shredded look. First time users of Trenbolone may start as low as 200mg Tren weekly to experience its powerful effects. More adventuresome users may double that dosage to 400mg Tren weekly.

References

Tissue selectivity and potential clinical applications of trenbolone (17beta-hydroxyestra-4,9,11-trien-3-one): A potent anabolic steroid with reduced androgenic and estrogenic activity.

17{beta}-Hydroxyestra-4,9,11-trien-3-one (trenbolone) exhibits tissue selective anabolic activity: effects on muscle, bone, adiposity, hemoglobin, and prostate.

Effect of trenbolone acetate on protein synthesis and degradation rates in fused bovine satellite cell cultures.
 
Am J Physiol Endocrinol Metab. 2011 Apr;300(4):E650-60. Epub 2011 Jan 25.

17{beta}-Hydroxyestra-4,9,11-trien-3-one (trenbolone) exhibits tissue selective anabolic activity: effects on muscle, bone, adiposity, hemoglobin, and prostate.

Yarrow JF, Conover CF, McCoy SC, Lipinska JA, Santillana CA, Hance JM, Cannady DF, Vanpelt TD, Sanchez J, Conrad BP, Pingel JE, Wronski TJ, Borst SE.

VA Medical Center, Research - 151, 1601 SW Archer Rd., Gainesville, FL 32608-1197. jfyarrow@ufl.edu.
Abstract

Selective androgen receptor modulators (SARMs) now under development can protect against muscle and bone loss without causing prostate growth or polycythemia. 17B-Hydroxyestra-4,9,11-trien-3-one (trenbolone), a potent testosterone analog, may have SARM-like actions because, unlike testosterone, trenbolone does not undergo tissue-specific 5a-reduction to form more potent androgens. We tested the hypothesis that trenbolone-enanthate (TREN) might prevent orchiectomy-induced losses in muscle and bone and visceral fat accumulation without increasing prostate mass or resulting in adverse hemoglobin elevations. Male F344 rats aged 3 mo underwent orchiectomy or remained intact and were administered graded doses of TREN, supraphysiological testosterone-enanthate, or vehicle for 29 days. In both intact and orchiectomized animals, all TREN doses and supraphysiological testosterone-enanthate augmented androgen-sensitive levator ani/bulbocavernosus muscle mass by 35-40% above shams (P 0.001) and produced a dose-dependent partial protection against orchiectomy-induced total and trabecular bone mineral density losses (P < 0.05) and visceral fat accumulation (P < 0.05). The lowest doses of TREN successfully maintained prostate mass and hemoglobin concentrations at sham levels in both intact and orchiectomized animals, whereas supraphysiological testosterone-enanthate and high-dose TREN elevated prostate mass by 84 and 68%, respectively (P < 0.01). In summary, low-dose administration of the non-5a-reducible androgen TREN maintains prostate mass and hemoglobin concentrations near the level of shams while producing potent myotrophic actions in skeletal muscle and partial protection against orchiectomy-induced bone loss and visceral fat accumulation. Our findings indicate that TREN has advantages over supraphysiological testosterone and supports the need for future preclinical studies examining the viability of TREN as an option for androgen replacement therapy.

PMID: 21266670 [PubMed - in process]
 
Steroids. 2010 Jun;75(6):377-89. Epub 2010 Feb 4.

Tissue selectivity and potential clinical applications of trenbolone (17beta-hydroxyestra-4,9,11-trien-3-one): A potent anabolic steroid with reduced androgenic and estrogenic activity.


Yarrow JF, McCoy SC, Borst SE.
Geriatric Research, Education & Clinical Center, VA Medical Center, Gainesville, FL 32608, United States. jfyarrow@ufl.edu

Abstract

Recently, the development of selective androgen receptor modulators (SARMs) has been suggested as a means of combating the deleterious catabolic effects of hypogonadism, especially in skeletal muscle and bone, without inducing the undesirable androgenic effects (e.g., prostate enlargement and polycythemia) associated with testosterone administration. 17beta-Hydroxyestra-4,9,11-trien-3-one (trenbolone; 17beta-TBOH), a synthetic analog of testosterone, may be capable of inducing SARM-like effects as it binds to androgen receptors (ARs) with approximately three times the affinity of testosterone and has been shown to augment skeletal muscle mass and bone growth and reduce adiposity in a variety of mammalian species. In addition to its direct actions through ARs, 17beta-TBOH may also exert anabolic effects by altering the action of endogenous growth factors or inhibiting the action of glucocorticoids. Compared to testosterone, 17beta-TBOH appears to induce less growth in androgen-sensitive organs which highly express the 5alpha reductase enzyme (e.g., prostate tissue and accessory sex organs). The reduced androgenic effects result from the fact that 17beta-TBOH is metabolized to less potent androgens in vivo; while testosterone undergoes tissue-specific biotransformation to more potent steroids, dihydrotestosterone and 17beta-estradiol, via the 5alpha-reductase and aromatase enzymes, respectively. Thus the metabolism of 17beta-TBOH provides a basis for future research evaluating its safety and efficacy as a means of combating muscle and bone wasting conditions, obesity, and/or androgen insensitivity syndromes in humans, similar to that of other SARMs which are currently in development.

Published by Elsevier Inc.

PMID: 20138077 [PubMed - indexed for MEDLINE]
 
Who's articles are these? I'm pretty sure I've read them before. tren is excellent, especially the lab I'm running now.
 
Who's articles are these? I'm pretty sure I've read them before. tren is excellent, especially the lab I'm running now.

I'm the original author of the first post. I updated the article a few days ago with some minor additions.

The following posts are abstracts of published studies on Trenbolone.
 
Nice work.

Very well written, I'm so used to people borrowing without giving credit, which we all have done to provide info. But it's nice to have posted from the original author.

Thanks for all your contributions.
 
Good read, the 16 week prep looks pretty intense. I would imagine you need a lot of experience with your AI's to keep bloat down with 1.5g's of test lol. Don't think I'll be trying that one, but good info none the less, never knew tren was ever even tried on humans, only cattle.
 
Nice work.

Very well written, I'm so used to people borrowing without giving credit, which we all have done to provide info. But it's nice to have posted from the original author.

Thanks for all your contributions.

this
 
What a fantastic post sir, thanks much for taking the time to inform the masses.

I'm considering Tren or Deca with my Test for the 2nd cycle. :)
 
What a fantastic post sir, thanks much for taking the time to inform the masses.

I'm considering Tren or Deca with my Test for the 2nd cycle. :)

I think the natural progression would be deca and test for a second cycle. Very popular, produces great gains over the long haul. Much easier on sides than tren tends to be.
 
CONCERNED_________HEAVYIRON______________

This is Fantastic info for an EXPERIENCED USER!!!!!!!!!!!!!!!!!!!!!!

My Concern lies here! You just provided a road map to disaster for every inexperienced kid thats on this site! ALTHOUGH your knowledge is great! Many of your posts I have praised!

AS ZEEK would say "Lets think about our audience here"

AND WOMEN_________ I would NEVER advocate the use of TREN!!!!!!!! Unless you want to look and speek like one of the female pros!!!!!!!!! Or your trying to become the MASCULINE part of a SAME SEX relation ship!!!!!!!!!!!

Just my 2 cents! The Article it self is solid! Unfortunatly I see several of these Kids running out jumping on the Tren band wagon, When thay have no business being there!
Not to mention EVEN though you pointed out PCT many wont do it!


TO ANYONE THAT DOSEN"T HAVE YEARS EXPERIENCE WITH AAS STAY AWAY FROM TREN!!!!!!!!!!

Use the above information to Educate your self! THAT IN NO WAY IMPLYS YOUR READY TO USE IT AFTER READING THIS
 
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CONCERNED_________HEAVYIRON______________

This is Fantastic info for an EXPERIENCED USER!!!!!!!!!!!!!!!!!!!!!!

My Concern lies here! You just provided a road map to disaster for every inexperienced kid thats on this site! ALTHOUGH your knowledge is great! Many of your posts I have praised!

AS ZEEK would say "Lets think about our audience here"

AND WOMEN_________ I would NEVER advocate the use of TREN!!!!!!!! Unless you want to look and speek like one of the female pros!!!!!!!!! Or your trying to become the MASCULINE part of a SAME SEX relation ship!!!!!!!!!!!

Just my 2 cents! The Article it self is solid! Unfortunatly I see several of these Kids running out jumping on the Tren band wagon, When thay have no business being there!
Not to mention EVEN though you pointed out PCT many wont do it!


TO ANYONE THAT DOSEN"T HAVE YEARS EXPERIENCE WITH AAS STAY AWAY FROM TREN!!!!!!!!!!

Use the above information to Educate your self! THAT IN NO WAY IMPLYS YOUR READY TO USE IT AFTER READING THIS

Yes, much of this information is for experienced users and will carry risks as stated in the article brother.


Also, please read my signature as it applies to every post I make.
 
Good thread. I'd rather have this thread than not because inexperience users can do much worse if they get no info.
 
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