I've done both Accutane and Retin-A. Accutane is some serious shit. I've never sweated like I did on that stuff, and it does fuck with your head (or it did with mine at 40 mg/ed). As a result, I was turned on to Retin-A, which in the more powerful gel form really worked miracles. Worked just as well as the Accutane, albeit on a slighly longer schedule. Most of the time, though, I get by using a salicylic acid-based toner, even when I'm on cycle. Johnson & Johnson and Neutrogena make good salicylic-based toners. Dial soap also is a big help. My problem is my back, on which nothing seems to work except a dark tan.