big mike dub
New member
I am planning on using clen in two week on/two week off cycles. And I want to know if I can use ephedrine on the two weeks off. Do they attatch to the same receptor site? Thanks
Clen and Eph receptor use
- Thread starter big mike dub
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big mike dub
New member
But they bind to the beta 1 or beta 2 receptors,sorry I don't know which. And that causes downregulation of the beta receptors, then the clen becomes uneffective. I was trying to find out if ephedrine binds to the same beta receptors as clen. If so, it would be a waste to use ephedrine on the off weeks of clen because the receptors would not be fresh. btw, this is how I remember it working, I'm no expert. 
big mike dub
New member
Cool thanks for your help.
big mike dub
New member
haha thanks bro. I see on the other thread you know that I have just stumbled upon that. Thanks again
China_Wall
New member
good plan to run the clen for 2 wks, then ECA stack (ephedrine, caffine, aspirin) during the other two weeks...
balboa270
Amateur Bodybuilder
taken from another unknown source
Since we´re speaking about beta-receptors and upregulation, here, let me address the claim that you can use ephedrine (or the ECA stack), alternating with clen, in order to avoid receptor downgrade. I´m not sure where this rumor came from, but it is totally incorrect.
To dispel this myth, lets examine ephedrine for a second. Remember when I said that using clenbuterol to stimulate the beta-2 receptors is like hitting a tack with a hammer? Well, Ephedrine is like a sledge-hammer, it hits the beta-2´s and everything around them. That´s because it´s not selective, but rather it stimulates other receptors to a great degree as well.
Anyway, one of those receptors that ephedrine hits is the Beta-2 (yeah...the same one as Clen). As you can see from the graph below (ephedrine is represented by the the solid circles), it reduced Beta-2-AndrenergicReceptor (what we call, in laymens terms, the "Beta-2 receptor") levels to 32% of the control level after 24 hours. Read this again:
Ephedrine, in this study, reduces Beta-2 receptor levels to 32% of control after 24 hours.
Since we´re speaking about beta-receptors and upregulation, here, let me address the claim that you can use ephedrine (or the ECA stack), alternating with clen, in order to avoid receptor downgrade. I´m not sure where this rumor came from, but it is totally incorrect.
To dispel this myth, lets examine ephedrine for a second. Remember when I said that using clenbuterol to stimulate the beta-2 receptors is like hitting a tack with a hammer? Well, Ephedrine is like a sledge-hammer, it hits the beta-2´s and everything around them. That´s because it´s not selective, but rather it stimulates other receptors to a great degree as well.
Anyway, one of those receptors that ephedrine hits is the Beta-2 (yeah...the same one as Clen). As you can see from the graph below (ephedrine is represented by the the solid circles), it reduced Beta-2-AndrenergicReceptor (what we call, in laymens terms, the "Beta-2 receptor") levels to 32% of the control level after 24 hours. Read this again:
Ephedrine, in this study, reduces Beta-2 receptor levels to 32% of control after 24 hours.
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