Nutropin Depot is a unique form of synthetic rhGH made by Genentech, the first pharmaceutical company to obtain FDA approval for the medical use of GH back in 1979.
Like all human GH, Depot has 191 amino acid residues and a molecular weight of 22,125 daltons. It's the delivery system that makes it special. When reconstituted, the GH molecules are microencapsulated in solution. The capsules are of varying thickness, and therefore release in a timed fashion.......like self-dissolving sutures. One injection is supposed to last 4 weeks, delivering an average 2.25iu GH daily. Actually, some of the Depot is non-encapsulated, and a relatively substantial dose is released in the first week....... you can definitely feel it. Since it is self-tapering, natural production of endogenous GH is gradually restored to normal toward the end of the month.
For those simply seeking to maintain the lean body composition afforded by supplemental GH, one 22.5 kit every 4 weeks is fine. If you are new to GH and looking to make dramatic changes in lean mass, I would recommend using a 22.5 kit every 3 weeks, or an 18mg kit every 2 weeks until the desired results are achieved......or add in a daily injection of regular GH after the first week.
I have used Nutropin Depot exclusively for almost a year. I used regular GH for 4 years straight prior to starting the Depot. The Depot is simply the best, most potent rhGH I have tried. Either it is of superior quality, or it is overdosed.....damn good stuff.
I have no experience with Supra, but I have to say.....I'm a bit skeptical. First of all, it is said that it can be kept at room temperature. The only rhGH patented for this is Serono. Could an underground lab accomplish this where no other major pharmaceutical company can? Heck, they can't even get the labels straight on the vials. And no other company of any size has duplicated the microencapsulation for timed release. And I see brothers post that Supra can be injected with an insulin dart........no way with the encapsulated solution. Depot requires a 21 gauge pin, and even those will clog unless you inject quickly.
But here's the other side of it, to be fair. Supra does make some darn good products. I have used several of the steroid preparations, and liked them. The good news here is that there are some fine brothers trying the GH right now........Trev, Fonz, ulter and others who enjoy great reputations. I look forward to the final reports from these gentlemen.
In the meantime, Depot is my preferred brand. It is not approved for Hormone Replacement Therapy (HRT), only for growth deficient children, so no script yet. I pay blackmarket retail like evryone else......and it's worth every penny to this old man.
