its my 2 week using anadrol, test and deca. I decided to run 500 through-out the cycle to prevent testicle shrinkage. However that didnt help. My testicles have shrunk to the size of raisins. Yesterday i injected 1500 hcg. Now my left testicle is back to its normal size, but for some reasone feels like jello to the touch (i can hardly feel it, its like its just water or something), and my right testicle is still the size of a raisin! i am pretty freaked about my right testicle not coming back, whats going on? should i do high doses of hcg for the next few days?
right testicle wont come back!
- Thread starter slava
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JohnnyB
Community Veteran
Don't do the high doses, go with small doses, here's some info that'll help.
Posted by hhajdo
Differential effect of single high dose and divided small dose administration of human chorionic gonadotropin on Leydig cell steroidogenic desensitization.
Smals AG, Pieters GF, Boers GH, Raemakers JM, Hermus AR, Benraad TJ, Kloppenborg PW.
This study compared the effect of a single high dose of hCG (1500 IU) with that of the same dose administered in multiple small doses (300 IU, once daily for 5 days) on Leydig cell steroidogenesis. Administration of a single high dose of hCG to seven healthy men raised the mean plasma testosterone (T) level to peak levels 2.1 +/- 0.2 (SEM) X the baseline value at 48 h. Thereafter plasma T decreased to below normal (0.7 +/- 0.1 X baseline) 7 days after the injection. The mean 17-hydroxyprogesterone (17-OHP) level peaked at 24 h (2.5 +/- 0.2 X baseline) and then also fell to a nadir value of 0.6 +/- 0.2 X baseline on day 7. Reflecting the early accumulation of 17-OHP over T, the 17 OHP/T ratio reached its maximum (1.6 +/- 0.1 X baseline) at 24 h at the same time when plasma estradiol [(E2) 4.4 +/- 0.6 X baseline] and the ratio E2/T (2.7 +/- 0.3 X baseline) achieved their maximal values. Administration of 1500 IU hCG in five divided doses of 300 IU daily increased the mean plasma T levels to peak value of 2.1 +/- 0.2 X baseline at 5 days and the levels remained elevated thereafter. The response of T as reflected by the area under the curve was almost twice as great as in the single dose study (2844 +/- 360 vs. 1647 +/- 214). In contrast to the single high dose experiment, mean plasma 17-OHP levels in the divided dose protocol did not peak at 24 h but only gradually increased. As the increase of T exceeded the 17-OHP increase at almost all time intervals, no accumulation of 17-OHP over T occurred as in the single dose experiment. Instead the 17-OHP/T ratio fell to a nadir value of 0.6 +/- 0.1 X baseline on day 7. The initial E2 peak was absent in the divided dose protocol and the E2/T ratio only marginally increased. Considering both experiments together a close relation was found between the hCG-induced increases in E2 and 17-OHP (r = +0.88, P less than 0.001), as well as the ratio 17 OHP/T (r = +0.64, P less than 0.02).
JohnnyB
Posted by hhajdo
Differential effect of single high dose and divided small dose administration of human chorionic gonadotropin on Leydig cell steroidogenic desensitization.
Smals AG, Pieters GF, Boers GH, Raemakers JM, Hermus AR, Benraad TJ, Kloppenborg PW.
This study compared the effect of a single high dose of hCG (1500 IU) with that of the same dose administered in multiple small doses (300 IU, once daily for 5 days) on Leydig cell steroidogenesis. Administration of a single high dose of hCG to seven healthy men raised the mean plasma testosterone (T) level to peak levels 2.1 +/- 0.2 (SEM) X the baseline value at 48 h. Thereafter plasma T decreased to below normal (0.7 +/- 0.1 X baseline) 7 days after the injection. The mean 17-hydroxyprogesterone (17-OHP) level peaked at 24 h (2.5 +/- 0.2 X baseline) and then also fell to a nadir value of 0.6 +/- 0.2 X baseline on day 7. Reflecting the early accumulation of 17-OHP over T, the 17 OHP/T ratio reached its maximum (1.6 +/- 0.1 X baseline) at 24 h at the same time when plasma estradiol [(E2) 4.4 +/- 0.6 X baseline] and the ratio E2/T (2.7 +/- 0.3 X baseline) achieved their maximal values. Administration of 1500 IU hCG in five divided doses of 300 IU daily increased the mean plasma T levels to peak value of 2.1 +/- 0.2 X baseline at 5 days and the levels remained elevated thereafter. The response of T as reflected by the area under the curve was almost twice as great as in the single dose study (2844 +/- 360 vs. 1647 +/- 214). In contrast to the single high dose experiment, mean plasma 17-OHP levels in the divided dose protocol did not peak at 24 h but only gradually increased. As the increase of T exceeded the 17-OHP increase at almost all time intervals, no accumulation of 17-OHP over T occurred as in the single dose experiment. Instead the 17-OHP/T ratio fell to a nadir value of 0.6 +/- 0.1 X baseline on day 7. The initial E2 peak was absent in the divided dose protocol and the E2/T ratio only marginally increased. Considering both experiments together a close relation was found between the hCG-induced increases in E2 and 17-OHP (r = +0.88, P less than 0.001), as well as the ratio 17 OHP/T (r = +0.64, P less than 0.02).
JohnnyB
DUANABOL
New member
Test, Deca, and Anadrol...guaranteed supression! This combination of steroids will shut you down very hard. You can make a full recovery, but it will take TIME. I advise you to take a good long break from the stuff. HCG isn't the answer. Get off the drugs and seek out natural remedies.
The jello feeling is normal with hcg..........keep taking the hcg as these guys have showed you and give it a week or two. When I am already supressed and then throw in hcg I get the same thing for a bit, just keep at it. That jello feeling will go away and your boys will come back. Not sure why it gets like that.....actually your the only other guy I've even heard mention it.
gotenks004
New member
good luck man
gator_mclusky
Man on a Mission
I may be the odd amn out but i dont use hcg at low doses thruout....just never felyt comfortable using it for that long even at low doses.( I know and respect Swales opinion BTW) As we know everyones different and when my nuts shrink...i spread out 5000 i.u.s over 4 days and Bam!!!back in business.This has worked for me for over 10 yrs.
Gator
Gator
Since there really isn't a lot of research done on hcg they way we use it we get forced to use the trial and error method. This has worked for me....and your way is working for you......so the main thing is that we both have nuts 
When you do the larger dose for a week.......assuming you still stay "on" for a while, how long does it take for them to shrink down again?
When you do the larger dose for a week.......assuming you still stay "on" for a while, how long does it take for them to shrink down again?
blue_pill
New member
is it odd that one side has had some response to HCG and the other hasn't?
I would be worried about such a size decrease unilaterally that was unresponsive to HCG and showed no recovery on a par with the opposite side.
There is a chance of a vascular accident like a testicular torsion but this is quite a rare occurence at a distance from puberty even if you are playing around with the size of your nuts using Anabolic Androgenic Steroids (AAS) and HCG. If in any doubt get checked out by your urologist, its the safest thing. You have to bare in mind all the caveats on steroidology about disclosure of your Anabolic Androgenic Steroids (AAS) use if you rely on healthcare insurance to pay your bills, but as I've posted before- you need to give your doctors as much information as you can to help you!
I would be worried about such a size decrease unilaterally that was unresponsive to HCG and showed no recovery on a par with the opposite side.
There is a chance of a vascular accident like a testicular torsion but this is quite a rare occurence at a distance from puberty even if you are playing around with the size of your nuts using Anabolic Androgenic Steroids (AAS) and HCG. If in any doubt get checked out by your urologist, its the safest thing. You have to bare in mind all the caveats on steroidology about disclosure of your Anabolic Androgenic Steroids (AAS) use if you rely on healthcare insurance to pay your bills, but as I've posted before- you need to give your doctors as much information as you can to help you!
Trainwrek
Juggernaut
Shit, I had more than a dull ache. Once while on post cycle therapy (pct) my left nut hurt so bad that I went to the DR cuz I thought something was wrong. After he cleared me, I went home and slapped myself because I realized what it was. Even with this, I've never lost my libido during or after any cycle. Even the first couple I did at 18 and 19 when I didn't know what a post cycle therapy (pct) was, I was still a champ after cycle.
Spongy
I am banned!
sorry bro, this thread is almost 8 years old. I would recommend starting your own thread if you have questions. A lot of research has come out over the last few years.
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