So you are saying you can run 2.5mg of Letro for the 1st two weeks if you can tolerate it? Then what? Taper down to how much for how long? There is a thread that says even after the gyno is gone to stay at 2.5mg for another 4-7 days to make sure then taper down to prevent estro rebound. What do you think?
Pramipexole and Letro in an attempt to rid of gyno lumps
- Thread starter wolfman010
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So you are saying you can run 2.5mg of Letro for the 1st two weeks if you can tolerate it? Then what? Taper down to how much for how long? There is a thread that says even after the gyno is gone to stay at 2.5mg for another 4-7 days to make sure then taper down to prevent estro rebound. What do you think?
dont taper just take 2-3 days off and then switch to exemestane (run 12.5mg per day for 1-2 days-- for crossover-- then bump to 25mg)
exemestane best if taken with high fat meal
THE-DET-OAK
IncreasedMyT @ ULV
Thats good info.
Why exemestane vs Nolva? The protocol I was recommended said to take nolva to prevent the estro rebound. Not arguing with you just want to know the thinking behind it.
Thanks for your input!
wolfman010
New member
Hey guys, just wanted to give an update on my thread. I am starting to see some changes. I have been at 2.5mg a day of letro and .5mg of prami a day for a couple weeks and I think I might start to back it down.
I have Nolva, should I just stop the letro and start the Nolva for rebound? I dont want to buy anything else since I already have Nolva....
I have Nolva, should I just stop the letro and start the Nolva for rebound? I dont want to buy anything else since I already have Nolva....
will again state, dont reccomend nolva as follow up. why are you backing down? also you should be increasing prami, unless sides are an issue.
even if you back down the dose of letrozole, until you come off you wont need anything for rebound. reccomend exemestane or AIFM to follow it with. both suicidal inhibitors (thus not subject to rebound)
wolfman010
New member
I was just backing down to 1.25mg a day because everyone was telling me that 2.5 was too high. I am going to continue running 1.25 for awhile.
So, when I decide to stop, I just go right into exemestane? What dosage and for how long?
I am taking .5mg/day of prami. How high should I go?
So, when I decide to stop, I just go right into exemestane? What dosage and for how long?
I am taking .5mg/day of prami. How high should I go?
MOE from H.P.
New member
hey wolfman, i have a marble sized lump behind my left nipple. i have 2.5mg letro tablets, you said youwere taking 1.25mg but for how long to get rid of this lump?
wolfman010
New member
until it's gone. I'm not the one to give advice, I have been getting mine from the other members on this thread, I think that question might have been answered somewhere in here.
wolfman010
New member
Macro can you comment on this?
take a couple days off then hit the exem.
you can run 2.5 so long as you dont have libido or joint dryness issues (you can even run then, but really only if its just libido, joint dryness can interfere with training... libido is only needed... if you need it-- so its more optional-- extremely important but optional).
with prami, generally think 1mg to 1.5mg is where benefit for regression peaks out. not everyone can go that high, and some people can jump up to that and others have to go very slow.
the main issue, other than immeadiate nausea issues, to watch out for with increases (especially large increases in prami dose) is blood sugar, both hyper and hypoglycemia can occur. especially if water intake is not stellar. keep in mind that prami will tend to suppress thirst, so you have to remember to drink. also high sodium, and insufficient potassium with the typical high protein diet makes hyperglycemic issues more common.
as a general rule, prami aside, potassium should be at least twice sodium, 4 times being preferable.
you can run 2.5 so long as you dont have libido or joint dryness issues (you can even run then, but really only if its just libido, joint dryness can interfere with training... libido is only needed... if you need it-- so its more optional-- extremely important but optional).
with prami, generally think 1mg to 1.5mg is where benefit for regression peaks out. not everyone can go that high, and some people can jump up to that and others have to go very slow.
the main issue, other than immeadiate nausea issues, to watch out for with increases (especially large increases in prami dose) is blood sugar, both hyper and hypoglycemia can occur. especially if water intake is not stellar. keep in mind that prami will tend to suppress thirst, so you have to remember to drink. also high sodium, and insufficient potassium with the typical high protein diet makes hyperglycemic issues more common.
as a general rule, prami aside, potassium should be at least twice sodium, 4 times being preferable.
wolfman010
New member
My water intake is very good and I keep sodium to a minimum. I'm on the CHA diet right now so my blood sugar levels should be relatively stable. Will increase to 1mg and see how I feel...thanks Macro
wolfman010
New member
Macro, what dosage and how long should the exem be run after the letro?
generally 25mg.
depends on how long its needed... and dose can also be reduced as times goes on.
aromatase issues can be due to breast tissue, female pattern fat, liver issues as well as aromatase polymorphism (thats most of them, there are others).
if you have any of the above, you will want to run some amount of exemestane until you can eliminate them. with respect to the last, pretty much a lifetime commitment ro estrogen suppression
depends on how long its needed... and dose can also be reduced as times goes on.
aromatase issues can be due to breast tissue, female pattern fat, liver issues as well as aromatase polymorphism (thats most of them, there are others).
if you have any of the above, you will want to run some amount of exemestane until you can eliminate them. with respect to the last, pretty much a lifetime commitment ro estrogen suppression
wolfman010
New member
So can I run Prami forever for the GH boosting benefits?
that is a bit of an unknown, can say that well past 8 months of consistent high dose use, users still reporting GH effects at same level.
wolfman010
New member
Macro, instead of going from letro to exemestane, can I just taper the letro off for a couple weeks?
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