careful zeek
before u go to wild on dosage u should have a read on this m8!
Activation of nuclear hormone receptor peroxisome proliferator***8211;activated receptor-***948; accelerates intestinal adenoma growth
Rajnish A Gupta1, Dingzhi Wang1, Sharada Katkuri1, Haibin Wang2, Sudhansu K Dey2 & Raymond N DuBois1,2,3
Abstract
We treated Apcmin mice, which are predisposed to intestinal polyposis, with a selective synthetic agonist of peroxisome proliferator***8211;activated receptor-***948; (PPAR-***948
. Exposure of Apcmin mice to the PPAR-***948; ligand GW501516 resulted in a significant increase in the number and size of intestinal polyps. The most prominent effect was on polyp size; mice treated with the PPAR-***948; activator had a fivefold increase in the number of polyps larger than 2 mm. Our results implicate PPAR-***948; in the regulation of intestinal adenoma growth.
this link has more information a more recent,if u wanna call 2007 recent lol
carcin.oxfordjournals.org/content/28/12/2641.full