Tren . What do you guys personally notice/get from it

[THE-DET-OAK]

Sorry bro long day. All those posts weren't directed at you either. Just loading up this thread with info to get views, activity.

The only action I can explain is secondary to the HPGA process, which is conversion rates. IE since Tren is as suppressive as DHT or more suppressive it is one of the few things that suppress it. Just like its suppressive effects on aromatase. It is also more suppressive than estrogen, unlike testosterone.

Sorry thought I said that a few times.

As for the high estradiol readings I don't believe in coincidences and think that happens because Tren actually acts more like an estrogen than it does an androgen.

Not to mention is has almost no affinity to the PGR so for me that throws the whole prolactin argument out the window and the only things left really for all these post cycle limp noodles is low DHT and Estrogen. Low meaning suppressed not necessarily clinically low.

 

[THE-DET-OAK]

BTW that is the second time you said "labs like that happen all the time".....which may be true, like the DNP and TNP convo in other thread, although I certainly never see it.

 

[THE-DET-OAK]

Thoughts on Tren acting like an estrogen anyone? IM gonna step out of this thread, please keep it going

 

[Onk]

Ok I give. For someone that doesn't work for IMT, how do you know do much about their clients and their labs, whilst you aren't a qualified medical professional? I imagine US confidentiality laws prohibit that kind of activity and it's very strange that you're admitting to breaking privacy so openly, if so.

 

[THE-DET-OAK]

 

[IMT staff]

Ok I give. For someone that doesn't work for IMT, how do you know do much about their clients and their labs, whilst you aren't a qualified medical professional? I imagine US confidentiality laws prohibit that kind of activity and it's very strange that you're admitting to breaking privacy so openly, if so.

Sorry to be the bearer of bad news but I didn't see OAK share any specifics. Also unless you are aware of something we are not, then anyone can show anyone their lab work results. It is up to them. Making a medical diagnoses/decision is something different altogether. Our physicians do that.

Thank you

 

[Onk]

Sorry to be the bearer of bad news but I didn't see OAK share any specifics. Also unless you are aware of something we are not, then anyone can show anyone their lab work results. It is up to them. Making a medical diagnoses/decision is something different altogether. Our physicians do that.

Thank you

He hasn't shared specifics but aludes to knowing them. Also, he makes out that he sees the results on IMT side and not from clients sharing with him, which is when IMT is breaking patient confidentiality.

Good job logging in just as DET logs out. Tag teamed in at the right time to try and back him up. Very suspect given bigben's earlier assumption that you're the same person.

 

[IMT staff]

I find it hilarious your pretending to know what your talking about.

 

[THE-DET-OAK]

He hasn't shared specifics but aludes to knowing them. Also, he makes out that he sees the results on IMT side and not from clients sharing with him, which is when IMT is breaking patient confidentiality.

Good job logging in just as DET logs out. Tag teamed in at the right time to try and back him up. Very suspect given bigben's earlier assumption that you're the same person.

Seriously your a douche bag liberal moocher. Instead of acting like a little bitch why don't you answer some of the questions I posed?

OH THATS RIGHT YOU DONT KNOW YOUR ASS FROM A HOLE IN THE GROUND haha

 

[Dreaded Pirate Roberts]

Whats with the hostility. Who needs a spanking. Seriously just can it. I get the fact that everyone has to be the know it all. I promise you I have forgotten more than you know but who cares. Get over it.

 

[THE-DET-OAK]

 

[THE-DET-OAK]

Can we get back to whether or not Tren actually acts like an estrogen in the human body suppressing all hormones it steals receptors from including DHT?

This is a hot topic and needs to be debated at length.

Here is a cool study showing both Tren and DHT are more suppressive than estradiol. This is besides the fact it would obviously suppress DHT conversion and aromatase.

Abstract
Twenty acutely castrated bulls were used to investigate the role of androgenic and oestrogenic steroids in the feedback control of LH secretion. The effects of 5 alpha-dihydrotestosterone (DHT) or the growth stimulants trenbolone acetate (TBA) or oestradiol-17 beta (OE2) on serum LH secretory profiles were measured. In addition, pituitary LH responses to exogenous LH releasing hormone (LHRH) were determined to differentiate between hypothalamic and pituitary sites of steroid action. At the time of castration, two groups of animals were given implants of either 45 mg OE2 or 200 mg TBA. Another group received equivalent to 30 mg daily injections of DHT. Control steers showed an increase in LH from 2.4 +/- 0.5 (S.E.M.) micrograms/l to 7.0 +/- 0.5 micrograms/l during the week after castration. Treatment with DHT and TBA prevented the post-castration rise in serum LH. In contrast, steers given implants of OE2 showed a significantly greater increase in LH than controls 1 day after castration, but by day 5 LH declined in the OE2-treated group to precastration values. Five weeks after castration control steers secreted LH in pulses at intervals of 40-50 min and with an amplitude of 4.2 +/- 0.4 micrograms/l. Pulses were not detected in the LH profiles of the steroid-treated steers. Dihydrotestosterone and TBA significantly reduced pituitary LH responses to exogenous LHRH, whereas steers receiving OE2 showed LH responses to LHRH which were similar to those observed in castrated controls. These results support the hypothesis that androgenic and oestrogenic components participate separately in the feedback control of LH secretion in the bull.(ABSTRACT TRUNCATED AT 250 WORDS)



Suppression of LH secretion by oestradiol, dihydrotestosterone and trenbolone acetate in the acutely castrated bull. - PubMed - NCBI

 

[halfwit]

Can we get back to whether or not Tren actually acts like an estrogen in the human body suppressing all hormones it steals receptors from including DHT?

This is a hot topic and needs to be debated at length.

My thought on this is that as tren doesn't aromatize, and estradiol is needed for hypertrophy. As it is suppressive, and does not aromatize, there wouldn't be any mechanism I can think of to replace the needed hormone.

Short reply, but waiting in the dentist's office before the gym lol.

 

[THE-DET-OAK]

Does it not aromatize because it does not need to since it has a much higher binding affinity?

For instance we know it does not convert to DHT either yet we all know Tren will make most guys hair fall out.

 

[halfwit]

Does it not aromatize because it does not need to since it has a much higher binding affinity?

Aromatase just doesn't recognize it. Kind of like DHT derivatives; which is odd as the other common 19-nor DOES aromatize a little.

 

[THE-DET-OAK]

EXACTLY, so with that and its next to no affinity to PGR there has to be something else at play.

Throw in the false E readings and thats just too many coincidences for me

 

[halfwit]

EXACTLY, so with that and its next to no affinity to PGR there has to be something else at play.

Throw in the false E readings and thats just too many coincidences for me

When I get home in a few hours, I'll see if I can't find the ECLIA paper on metabolites (unless someone else has it) causing false readings.

I remember having a pretty in depth discussion awhile ago on the progestin activity, but I'd have to again to find the process in its entirety.

 

[THE-DET-OAK]

I would love to see it when you have time.

For PGR though some veterinarian studies show it doesn't even have a higher binding affinity than progesterone, I think its like 100 times less or so.

 

[Megatron28]

When I get home in a few hours, I'll see if I can't find the ECLIA paper on metabolites (unless someone else has it) causing false readings.

I remember having a pretty in depth discussion awhile ago on the progestin activity, but I'd have to again to find the process in its entirety.

Here is the paper on Nandrolone. I am not aware of any tren studies on humans so I don't think you will find something similar showing how tren affects ECLIA blood work.

http://www.accessdata.fda.gov/cdrh_docs/reviews/k093421.pdf

 

[Samson4]

Oh I forgot to mention bad breath. I'm not sure why but everytime I run tren I get bad breath. It's not hygeine, I've never had a cavity in my life. It's not hydration, I drink about a gallon of water when I'm not on cycle. When I am, it's usually about 1.5.